Guy Leonard works with comparative genomics, phylogenomics and genome assembly with an interest in the evolutionary relationships of eukaryotes and the cellular & genomic innovations of the diversity of eukaryotic cells. This work has led him to specifically look at the prevalence of gene fusion & fission events across the eTOL. More recently he has been trying to understand the adaptations and evolutionary history of an oomycete-relative, Hyphochytrium catenoides and a fungal-eye complex present in chytrid fungi, specifically in Blastocladiella emersonii He also supports other bioinformatics work within the group, providing; advice on sequencing, genome and transcriptome assembly, genome annotation, phylogenomic tree reconstruction, 18S amplicon analysis with DADA2, all along with mainting a set of web-based BLAST servers, this website, and an HPC environment for the group's use!
- Controlled sampling of ribosomally active protistan diversity in sediment-surface layers identifies putative players in the marine carbon sink. Rodríguez-Martínez, Leonard, Milner, Sudek, Conway, Moore, Hudson, Mahé, Keeling, Santoro, Worden, Richards. 2020, ISME J, doi.org/10.1038/s41396-019-0581-y
- Unexpected mitochondrial genome diversity revealed by targeted single-cell genomics of heterotrophic flagellated protists. Jeremy G Wideman, Adam Monier, Raquel Rodríguez-Martínez, Guy Leonard, Emily Cook, Camille Poirier, Finlay Maguire, David S Milner, Nicholas AT Irwin, Karen Moore, Alyson E Santoro, Patrick J Keeling, Alexandra Z Worden, Thomas A Richards. Nature Microbiology 5 (1), 154-165. https://doi.org/10.1038/s41564-019-0605-4
- Sequenceserver: a modern graphical user interface for custom BLAST databases. Anurag Priyam, Ben J Woodcroft, Vivek Rai, Ismail Moghul, Alekhya Munagala, Filip Ter, Hiten Chowdhary, Iwo Pieniak, Lawrence J Maynard, Mark Anthony Gibbins, HongKee Moon, Austin Davis-Richardson, Mahmut Uludag, Nathan S Watson-Haigh, Richard Challis, Hiroyuki Nakamura, Emeline Favreau, Esteban A Gómez, Tomás Pluskal, Guy Leonard, Wolfgang Rumpf, Yannick Wurm. Molecular biology and evolution 36 (12), 2922-2924. https://doi.org/10.1093/molbev/msz185
- Comparative genomic analysis of the ‘pseudofungus’ Hyphochytrium catenoides. Guy Leonard, Aurélie Labarre, David S Milner, Adam Monier, Darren Soanes, Jeremy G Wideman, Finlay Maguire, Sam Stevens, Divya Sain, Xavier Grau-Bové, Arnau Sebé-Pedrós, Jason E Stajich, Konrad Paszkiewicz, Matthew W Brown, Neil Hall, Bill Wickstead, Thomas A Richards. Open biology 8 (1), 170184. https://doi.org/10.1098/rsob.170184